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Santa Fe Station Hotel Casino Map Santa Fe Station Hotel Casino Location Map Address: 4949 N Rancho Dr, Las Vegas, Nevada, 89130 Location: Northwest, 15 miles from the Strip Direction: From I-15 to the I-95 West. Exit Rancho Dr. and turn right. The hotel will be on the left. hotel Santa Fe Station Hotel Casino Santa Fe Station Hotel Casino Luxurious hotel accommodations with 200 guest rooms, delicious dining facilities, FREE live entertainment, full casino, 60 lanes bowling center, Kids Quest children activity center and convention meeting spaces.